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The PBMCs of allergic rhinitis patients pre-treated with luteolin (1.25, 2.5, 5 g/mL) reduced CD4+IL-4- secreting cells at 5 g/mL, confirming luteolins inhibition of Th2 cells expression [162]

Aging Cell 22 , e13936 (2023)

It has however been used for years and there are papers that have noted that there are no risks that would disallow the usage

Conclusions NAD+ depletion is one of the primary pathogenesis of heart disease, and NAD+ supplementation has shown therapeutic potential for restoring healthy metabolism and physiological functions